IIT Bombay’s DNA Shields Revive Failing Antibiotics
IIT Bombay scientists develop DNA aptamers blocking bacterial resistance enzymes, reviving common antibiotics to fight deadly drug-resistant infections.
Prof Ruchi Anand
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IIT Bombay pioneers DNA aptamer strategy to restore antibiotic effectiveness against resistant bacteria
IIT Bombay researchers Prof Ruchi Anand and Prof P I Pradeepkumar developed DNA aptamers – short synthetic nucleic acid strands – to block bacterial resistance enzymes, resensitizing drug-resistant pathogens to existing antibiotics. Unlike developing new drugs, this practical approach leverages known antibiotic safety profiles while addressing the global antimicrobial resistance crisis through stable, modifiable aptamers.